TMPO Back

thymopoietin

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NCBI Description of TMPO
The protein encoded by this gene resides in the nucleus and may play a role in the assembly of the nuclear lamina, and thus help maintain the structural organization of the nuclear envelope. It may function as a receptor for the attachment of lamin filaments to the inner nuclear membrane. Mutations in this gene are associated with dilated cardiomyopathy. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.

Community Annotation of TMPO Add / Edit TMPO: Annotations

No community annotations yet for TMPO.
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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

TMPO is highly significantly mutated in
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TMPO is significantly mutated in
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TMPO is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for TMPO