TMOD2 Back

tropomodulin 2 (neuronal)

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NCBI Description of TMOD2

This gene encodes a neuronal-specific member of the tropomodulin family of actin-regulatory proteins. The encoded protein caps the pointed end of actin filaments preventing both elongation and depolymerization. The capping activity of this protein is dependent on its association with tropomyosin. Alternatively spliced transcript variants encoding different isoforms have been described.

Community Annotation of TMOD2 Add / Edit TMOD2: Annotations

No community annotations yet for TMOD2.
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Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


TMOD2 is highly significantly mutated in
TMOD2 is significantly mutated in
TMOD2 is near significance in

Click on a tumor type to see its full list of significant genes.

Data details

Mutation list for TMOD2