TMCO1 Back

transmembrane and coiled-coil domains 1

External References:      Wikipedia GeneCards HUGO COSMIC Google Scholar

NCBI Description of TMCO1
This locus encodes a transmembrane protein. Mutations at this locus have been associated with craniofacial dysmorphism, skeletal anomalies, and mental retardation. Mutations at this locus have also been associated with open angle glaucoma blindness. Alternatively spliced transcript variants have been described.

Community Annotation of TMCO1 Add / Edit TMCO1: Annotations

No community annotations yet for TMCO1.
Sort mutations by: Tumor type  Mutation type  Position  
Straightedge cursor Expand

Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

TMCO1 is highly significantly mutated in
(none)
TMCO1 is significantly mutated in
(none)
TMCO1 is near significance in
(none)

Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for TMCO1