TMCO1 Back

transmembrane and coiled-coil domains 1

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NCBI Description of TMCO1

This locus encodes a transmembrane protein. Mutations at this locus have been associated with craniofacial dysmorphism, skeletal anomalies, and mental retardation. Mutations at this locus have also been associated with open angle glaucoma blindness. Alternatively spliced transcript variants have been described.

Community Annotation of TMCO1 Add / Edit TMCO1: Annotations

No community annotations yet for TMCO1.
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Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


TMCO1 is highly significantly mutated in
TMCO1 is significantly mutated in
TMCO1 is near significance in

Click on a tumor type to see its full list of significant genes.

Data details

Mutation list for TMCO1