TMC2 Back

transmembrane channel-like 2

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NCBI Description of TMC2
This gene is considered a member of a gene family predicted to encode transmembrane proteins. The specific function of this gene is unknown; however, expression in the inner ear suggests that it may be crucial for normal auditory function. Mutations in this gene may underlie hereditary disorders of balance and hearing.

Community Annotation of TMC2 Add / Edit TMC2: Annotations

No community annotations yet for TMC2.
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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

TMC2 is highly significantly mutated in
(none)
TMC2 is significantly mutated in
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TMC2 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for TMC2