TM9SF2 Back

transmembrane 9 superfamily member 2

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NCBI Description of TM9SF2
This gene encodes a member of the transmembrane 9 superfamily. The encoded 76 kDa protein localizes to early endosomes in human cells. The encoded protein possesses a conserved and highly hydrophobic C-terminal domain which contains nine transmembrane domains. The protein may play a role in small molecule transport or act as an ion channel. A pseudogene associated with this gene is located on the X chromosome. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.

Community Annotation of TM9SF2 Add / Edit TM9SF2: Annotations

No community annotations yet for TM9SF2.
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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

TM9SF2 is highly significantly mutated in
(none)
TM9SF2 is significantly mutated in
(none)
TM9SF2 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for TM9SF2