TLX3 Back

T-cell leukemia homeobox 3

External References:      Wikipedia GeneCards HUGO COSMIC Google Scholar

NCBI Description of TLX3

RNX (HOX11L2, TLX3) belongs to a family of orphan homeobox genes that encode DNA-binding nuclear transcription factors. Members of the HOX11 gene family are characterized by a threonine-47 replacing cytosine in the highly conserved homeodomain (Dear et al., 1993 [PubMed 8099440]).[supplied by OMIM, Mar 2008].

Community Annotation of TLX3 Add / Edit TLX3: Annotations

No community annotations yet for TLX3.
Sort mutations by: Tumor type  Mutation type  Position  
Straightedge cursor Expand

Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

TLX3 is highly significantly mutated in
(none)
TLX3 is significantly mutated in
(none)
TLX3 is near significance in
(none)

Click on a tumor type to see its full list of significant genes.

Data details


Mutation list for TLX3