TKT Back

transketolase (Wernicke-Korsakoff syndrome)

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NCBI Description of TKT

This gene encodes a thiamine-dependent enzyme which plays a role in the channeling of excess sugar phosphates to glycolysis in the pentose phosphate pathway. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Community Annotation of TKT Add / Edit TKT: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

TKT is highly significantly mutated in
(none)
TKT is significantly mutated in
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TKT is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


Mutation list for TKT