TKT Back

transketolase (Wernicke-Korsakoff syndrome)

External References:      Wikipedia GeneCards HUGO COSMIC Google Scholar

NCBI Description of TKT

This gene encodes a thiamine-dependent enzyme which plays a role in the channeling of excess sugar phosphates to glycolysis in the pentose phosphate pathway. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Community Annotation of TKT Add / Edit TKT: Annotations

No community annotations yet for TKT.
Sort mutations by: Tumor type  Mutation type  Position  
Straightedge cursor Expand

Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


TKT is highly significantly mutated in
TKT is significantly mutated in
TKT is near significance in

Click on a tumor type to see its full list of significant genes.

Data details

Mutation list for TKT