TJP1 Back

tight junction protein 1 (zona occludens 1)

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NCBI Description of TJP1
This gene encodes a protein located on a cytoplasmic membrane surface of intercellular tight junctions. The encoded protein may be involved in signal transduction at cell-cell junctions. Two transcript variants encoding distinct isoforms have been identified for this gene.

Community Annotation of TJP1 Add / Edit TJP1: Annotations

No community annotations yet for TJP1.
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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

TJP1 is highly significantly mutated in
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TJP1 is significantly mutated in
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TJP1 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for TJP1