TIPARP Back

TCDD-inducible poly(ADP-ribose) polymerase

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NCBI Description of TIPARP

This gene encodes a member of the poly(ADP-ribose) polymerase superfamily. Studies of the mouse ortholog have shown that the encoded protein catalyzes histone poly(ADP-ribosyl)ation and may be involved in T-cell function. Alternative splicing results in multiple transcript variants.

Community Annotation of TIPARP Add / Edit TIPARP: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

TIPARP is highly significantly mutated in
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TIPARP is significantly mutated in
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TIPARP is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


Mutation list for TIPARP