TIMP4 Back

TIMP metallopeptidase inhibitor 4

External References:      Wikipedia GeneCards HUGO COSMIC Google Scholar

NCBI Description of TIMP4
This gene belongs to the TIMP gene family. The proteins encoded by this gene family are inhibitors of the matrix metalloproteinases, a group of peptidases involved in degradation of the extracellular matrix. The secreted, netrin domain-containing protein encoded by this gene is involved in regulation of platelet aggregation and recruitment and may play role in hormonal regulation and endometrial tissue remodeling.

Community Annotation of TIMP4 Add / Edit TIMP4: Annotations

No community annotations yet for TIMP4.
Sort mutations by: Tumor type  Mutation type  Position  
Straightedge cursor Expand

Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

TIMP4 is highly significantly mutated in
(none)
TIMP4 is significantly mutated in
(none)
TIMP4 is near significance in
(none)

Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for TIMP4