thyroid hormone responsive (SPOT14 homolog, rat)

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NCBI Description of THRSP

The protein encoded by this gene is similar to the gene product of S14, a rat gene whose expression is limited to liver and adipose tissue and is controlled by nutritional and hormonal factors. This gene has been shown to be expressed in liver and adipocytes, particularly in lipomatous modules. It is also found to be expressed in lipogenic breast cancers, which suggests a role in controlling tumor lipid metabolism.

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Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


THRSP is highly significantly mutated in
THRSP is significantly mutated in
THRSP is near significance in

Click on a tumor type to see its full list of significant genes.

Data details

Mutation list for THRSP