THBS3 Back

thrombospondin 3

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NCBI Description of THBS3
The protein encoded by this gene belongs to the thrombospondin family. Thrombospondin family members are adhesive glycoproteins that mediate cell-to-cell and cell-to-matrix interactions. This protein forms a pentameric molecule linked by a single disulfide bond. This gene shares a common promoter with metaxin 1. Alternate splicing results in coding and non-coding transcript variants.

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

THBS3 is highly significantly mutated in
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THBS3 is significantly mutated in
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THBS3 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for THBS3