TH1L Back

TH1-like (Drosophila)

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NCBI Description of TH1L

The NELF complex of proteins interacts with the DSIF protein complex to repress transcriptional elongation by RNA polymerase II. The protein encoded by this gene is an essential part of the NELF complex. Alternative translation initiation site usage results in the formation of two isoforms with different N-termini.

Community Annotation of TH1L Add / Edit TH1L: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

TH1L is highly significantly mutated in
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TH1L is significantly mutated in
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TH1L is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


Mutation list for TH1L