TGM6 Back

transglutaminase 6

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NCBI Description of TGM6
The protein encoded by this gene belongs to the transglutaminase superfamily. It catalyzes the cross-linking of proteins and the conjugation of polyamines to proteins. Mutations in this gene are associated with spinocerebellar ataxia type 35 (SCA35). Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Community Annotation of TGM6 Add / Edit TGM6: Annotations

No community annotations yet for TGM6.
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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

TGM6 is highly significantly mutated in
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TGM6 is significantly mutated in
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TGM6 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for TGM6