TFDP1 Back

transcription factor Dp-1

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NCBI Description of TFDP1

This gene encodes a member of a family of transcription factors that heterodimerize with E2F proteins to enhance their DNA-binding activity and promote transcription from E2F target genes. The encoded protein functions as part of this complex to control the transcriptional activity of numerous genes involved in cell cycle progression from G1 to S phase. Alternative splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 1, 15, and X.

Community Annotation of TFDP1 Add / Edit TFDP1: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

TFDP1 is highly significantly mutated in
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TFDP1 is significantly mutated in
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TFDP1 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


Mutation list for TFDP1