TFAP2C Back

transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma)

External References:      Wikipedia GeneCards HUGO COSMIC Google Scholar

NCBI Description of TFAP2C

The protein encoded by this gene is a sequence-specific DNA-binding transcription factor involved in the activation of several developmental genes. The encoded protein can act as either a homodimer or heterodimer with other family members and is induced during retinoic acid-mediated differentiation. It plays a role in the development of the eyes, face, body wall, limbs, and neural tube.

Community Annotation of TFAP2C Add / Edit TFAP2C: Annotations

No community annotations yet for TFAP2C.
Sort mutations by: Tumor type  Mutation type  Position  
Straightedge cursor Expand

Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

TFAP2C is highly significantly mutated in
(none)
TFAP2C is significantly mutated in
(none)
TFAP2C is near significance in
(none)

Click on a tumor type to see its full list of significant genes.

Data details


Mutation list for TFAP2C