External References:
Wikipedia
GeneCards
HUGO
COSMIC
Google Scholar
NCBI Description of TERF1 |
This gene encodes a telomere specific protein which is a component of the telomere nucleoprotein complex. This protein is present at telomeres throughout the cell cycle and functions as an inhibitor of telomerase, acting in cis to limit the elongation of individual chromosome ends. The protein structure contains a C-terminal Myb motif, a dimerization domain near its N-terminus and an acidic N-terminus. Two transcripts of this gene are alternatively spliced products. |
Community Annotation of TERF1 Add / Edit TERF1: Annotations
No community annotations yet for TERF1.
|
Figure notes
• "Mouse over" a mutation to see details. |
|
Click on a tumor type to see its full list of significant genes.
Data details