TECR Back

trans-2,3-enoyl-CoA reductase

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NCBI Description of TECR
This gene encodes a multi-pass membrane protein that resides in the endoplasmic reticulum, and belongs to the steroid 5-alpha reductase family. The elongation of microsomal long and very long chain fatty acid consists of 4 sequential reactions. This protein catalyzes the final step, reducing trans-2,3-enoyl-CoA to saturated acyl-CoA. Alternatively spliced transcript variants have been found for this gene.

Community Annotation of TECR Add / Edit TECR: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

TECR is highly significantly mutated in
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TECR is significantly mutated in
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TECR is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for TECR