TEAD1 Back

TEA domain family member 1 (SV40 transcriptional enhancer factor)

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NCBI Description of TEAD1

This gene encodes a ubiquitous transcriptional enhancer factor that is a member of the TEA/ATTS domain family. This protein directs the transactivation of a wide variety of genes and, in placental cells, also acts as a transcriptional repressor. Mutations in this gene cause Sveinsson's chorioretinal atrophy. Additional transcript variants have been described but their full-length natures have not been experimentally verified.

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Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


TEAD1 is highly significantly mutated in
TEAD1 is significantly mutated in
TEAD1 is near significance in

Click on a tumor type to see its full list of significant genes.

Data details

Mutation list for TEAD1