TCTN3 Back

tectonic family member 3

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NCBI Description of TCTN3
This gene encodes a member of the tectonic gene family which functions in Hedgehog signal transduction and development of the neural tube. Mutations in this gene have been associated with Orofaciodigital Syndrome IV and Joubert Syndrom 18. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Community Annotation of TCTN3 Add / Edit TCTN3: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

TCTN3 is highly significantly mutated in
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TCTN3 is significantly mutated in
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TCTN3 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for TCTN3