TCTN2 Back

tectonic family member 2

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NCBI Description of TCTN2
This gene encodes a type I membrane protein that belongs to the tectonic family. Studies in mice suggest that this protein may be involved in hedgehog signaling, and essential for ciliogenesis. Mutations in this gene are associated with Meckel syndrome type 8. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Community Annotation of TCTN2 Add / Edit TCTN2: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

TCTN2 is highly significantly mutated in
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TCTN2 is significantly mutated in
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TCTN2 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for TCTN2