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transcobalamin I (vitamin B12 binding protein, R binder family)

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NCBI Description of TCN1

This gene encodes a member of the vitamin B12-binding protein family. This family of proteins, alternatively referred to as R binders, is expressed in various tissues and secretions. This protein is a major constituent of secondary granules in neutrophils and facilitates the transport of cobalamin into cells.

Community Annotation of TCN1 Add / Edit TCN1: Annotations

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Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


TCN1 is highly significantly mutated in
TCN1 is significantly mutated in
TCN1 is near significance in

Click on a tumor type to see its full list of significant genes.

Data details

Mutation list for TCN1