transcription elongation regulator 1

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NCBI Description of TCERG1

This gene encodes a nuclear protein that regulates transcriptional elongation and pre-mRNA splicing. The encoded protein interacts with the hyperphosphorylated C-terminal domain of RNA polymerase II via multiple FF domains, and with the pre-mRNA splicing factor SF1 via a WW domain. Alternative splicing results in multiple transcripts variants encoding different isoforms.

Community Annotation of TCERG1 Add / Edit TCERG1: Annotations

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Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


TCERG1 is highly significantly mutated in
TCERG1 is significantly mutated in
TCERG1 is near significance in

Click on a tumor type to see its full list of significant genes.

Data details

Mutation list for TCERG1