TCEA2 Back

transcription elongation factor A (SII), 2

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NCBI Description of TCEA2
The protein encoded by this gene is found in the nucleus, where it functions as an SII class transcription elongation factor. Elongation factors in this class are responsible for releasing RNA polymerase II ternary complexes from transcriptional arrest at template-encoded arresting sites. The encoded protein has been shown to interact with general transcription factor IIB, a basal transcription factor. Two transcript variants encoding different isoforms have been found for this gene.

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

TCEA2 is highly significantly mutated in
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TCEA2 is significantly mutated in
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TCEA2 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for TCEA2