TBX20 Back

T-box 20

External References:      Wikipedia GeneCards HUGO COSMIC Google Scholar

NCBI Description of TBX20
This gene encodes a T-box family member. The T-box family members share a common DNA binding domain, termed the T-box, and they are transcription factors involved in the regulation of developmental processes. This gene is essential for heart development. Mutations in this gene are associated with diverse cardiac pathologies, including defects in septation, valvulogenesis and cardiomyopathy. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Community Annotation of TBX20 Add / Edit TBX20: Annotations

No community annotations yet for TBX20.
Sort mutations by: Tumor type  Mutation type  Position  
Straightedge cursor Expand

Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

TBX20 is highly significantly mutated in
(none)
TBX20 is significantly mutated in
(none)
TBX20 is near significance in
(none)

Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for TBX20