TBX20 Back

T-box 20

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NCBI Description of TBX20

This gene encodes a T-box family member. The T-box family members share a common DNA binding domain, termed the T-box, and they are transcription factors involved in the regulation of developmental processes. This gene is essential for heart development. Mutations in this gene are associated with diverse cardiac pathologies, including defects in septation, valvulogenesis and cardiomyopathy. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Community Annotation of TBX20 Add / Edit TBX20: Annotations

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Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


TBX20 is highly significantly mutated in
TBX20 is significantly mutated in
TBX20 is near significance in

Click on a tumor type to see its full list of significant genes.

Data details

Mutation list for TBX20