TBL2 Back

transducin (beta)-like 2

External References:      Wikipedia GeneCards HUGO COSMIC Google Scholar

NCBI Description of TBL2

This gene encodes a member of the beta-transducin protein family. Most proteins of the beta-transducin family are involved in regulatory functions. This protein is possibly involved in some intracellular signaling pathway. This gene is deleted in Williams-Beuren syndrome, a developmental disorder caused by deletion of multiple genes at 7q11.23.

Community Annotation of TBL2 Add / Edit TBL2: Annotations

No community annotations yet for TBL2.
Sort mutations by: Tumor type  Mutation type  Position  
Straightedge cursor Expand

Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


TBL2 is highly significantly mutated in
TBL2 is significantly mutated in
TBL2 is near significance in

Click on a tumor type to see its full list of significant genes.

Data details

Mutation list for TBL2