TBCC Back

tubulin folding cofactor C

External References:      Wikipedia GeneCards HUGO COSMIC Google Scholar

NCBI Description of TBCC
Cofactor C is one of four proteins (cofactors A, D, E, and C) involved in the pathway leading to correctly folded beta-tubulin from folding intermediates. Cofactors A and D are believed to play a role in capturing and stabilizing beta-tubulin intermediates in a quasi-native confirmation. Cofactor E binds to the cofactor D/beta-tubulin complex; interaction with cofactor C then causes the release of beta-tubulin polypeptides that are committed to the native state.

Community Annotation of TBCC Add / Edit TBCC: Annotations

No community annotations yet for TBCC.
Sort mutations by: Tumor type  Mutation type  Position  
Straightedge cursor Expand

Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

TBCC is highly significantly mutated in
(none)
TBCC is significantly mutated in
(none)
TBCC is near significance in
(none)

Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for TBCC