TBC1D8B Back

TBC1 domain family, member 8B (with GRAM domain)

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NCBI Description of TBC1D8B
This gene encodes a protein with a TBC (Tre-2/Bub2/CDC16) domain. Some mammalian proteins with this domain have been shown to function as Rab-GAPs by binding to specific Rab proteins and affecting their GTPase activity. Alternative splicing results in multiple transcript variants.

Community Annotation of TBC1D8B Add / Edit TBC1D8B: Annotations

No community annotations yet for TBC1D8B.
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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

TBC1D8B is highly significantly mutated in
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TBC1D8B is significantly mutated in
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TBC1D8B is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for TBC1D8B