TBC1D10C Back

TBC1 domain family, member 10C

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NCBI Description of TBC1D10C
The protein encoded by this gene has an N-terminal Rab-GTPase domain and a binding site at the C-terminus for calcineurin, and is an inhibitor of both the Ras signaling pathway and calcineurin, a phosphatase regulated by calcium and calmodulin. Genes encoding similar proteins are located on chromosomes 16 and 22. Multiple transcript variants encoding different isoforms have been found for this gene.

Community Annotation of TBC1D10C Add / Edit TBC1D10C: Annotations

No community annotations yet for TBC1D10C.
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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

TBC1D10C is highly significantly mutated in
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TBC1D10C is significantly mutated in
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TBC1D10C is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for TBC1D10C