TBC1D10B Back

TBC1 domain family, member 10B

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NCBI Description of TBC1D10B

Small G proteins of the RAB family (see MIM 179508) function in intracellular vesicle trafficking by switching from the GTP-bound state to the GDP-bound state with the assistance of guanine nucleotide exchange factors (GEFs; see MIM 609700) and GTPase-activating proteins (GAPs). TBC1D10B functions as a GAP for several proteins of the Rab family (Ishibashi et al., 2009 [PubMed 19077034]).[supplied by OMIM, Nov 2010].

Community Annotation of TBC1D10B Add / Edit TBC1D10B: Annotations

No community annotations yet for TBC1D10B.
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Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


TBC1D10B is highly significantly mutated in
TBC1D10B is significantly mutated in
TBC1D10B is near significance in

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Data details

Mutation list for TBC1D10B