TAPBPL Back

TAP binding protein-like

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NCBI Description of TAPBPL
Tapasin, or TAPBP (MIM 601962), is a member of the variable-constant Ig superfamily that links major histocompatibility complex (MHC) class I molecules to the transporter associated with antigen processing (TAP; see MIM 170260) in the endoplasmic reticulum (ER). The TAPBP gene is located near the MHC complex on chromosome 6p21.3. TAPBPL is a member of the Ig superfamily that is localized on chromosome 12p13.3, a region somewhat paralogous to the MHC.[supplied by OMIM, Mar 2008].

Community Annotation of TAPBPL Add / Edit TAPBPL: Annotations

No community annotations yet for TAPBPL.
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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

TAPBPL is highly significantly mutated in
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TAPBPL is significantly mutated in
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TAPBPL is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for TAPBPL