TAGLN Back

transgelin

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NCBI Description of TAGLN
The protein encoded by this gene is a transformation and shape-change sensitive actin cross-linking/gelling protein found in fibroblasts and smooth muscle. Its expression is down-regulated in many cell lines, and this down-regulation may be an early and sensitive marker for the onset of transformation. A functional role of this protein is unclear. Two transcript variants encoding the same protein have been found for this gene.

Community Annotation of TAGLN Add / Edit TAGLN: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

TAGLN is highly significantly mutated in
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TAGLN is significantly mutated in
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TAGLN is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for TAGLN