TAF1B Back

TATA box binding protein (TBP)-associated factor, RNA polymerase I, B, 63kDa

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NCBI Description of TAF1B

Initiation of transcription by RNA polymerase I requires the formation of a complex composed of the TATA-binding protein (TBP) and three TBP-associated factors (TAFs) specific for RNA polymerase I. This complex, known as SL1, binds to the core promoter of ribosomal RNA genes to position the polymerase properly and acts as a channel for regulatory signals. This gene encodes one of the SL1-specific TAFs.

Community Annotation of TAF1B Add / Edit TAF1B: Annotations

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Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


TAF1B is highly significantly mutated in
TAF1B is significantly mutated in
TAF1B is near significance in

Click on a tumor type to see its full list of significant genes.

Data details

Mutation list for TAF1B