TAF15 Back

TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa

External References:      Wikipedia GeneCards HUGO COSMIC Google Scholar

NCBI Description of TAF15
This gene encodes a member of the TET family of RNA-binding proteins. The encoded protein plays a role in RNA polymerase II gene transcription as a component of a distinct subset of multi-subunit transcription initiation factor TFIID complexes. Translocations involving this gene play a role in acute leukemia and extraskeletal myxoid chondrosarcoma, and mutations in this gene may play a role in amyotrophic lateral sclerosis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Community Annotation of TAF15 Add / Edit TAF15: Annotations

No community annotations yet for TAF15.
Sort mutations by: Tumor type  Mutation type  Position  
Straightedge cursor Expand

Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

TAF15 is highly significantly mutated in
(none)
TAF15 is significantly mutated in
(none)
TAF15 is near significance in
(none)

Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for TAF15