TACC3 Back

transforming, acidic coiled-coil containing protein 3

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NCBI Description of TACC3

This gene encodes a member of the transforming acidic colied-coil protein family. The encoded protein is a motor spindle protein that may play a role in stabilization of the mitotic spindle. This protein may also play a role in growth a differentiation of certain cancer cells.

Community Annotation of TACC3 Add / Edit TACC3: Annotations

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Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


TACC3 is highly significantly mutated in
TACC3 is significantly mutated in
TACC3 is near significance in

Click on a tumor type to see its full list of significant genes.

Data details

Mutation list for TACC3