SYVN1 Back

synovial apoptosis inhibitor 1, synoviolin

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NCBI Description of SYVN1

This gene encodes a protein involved in endoplasmic reticulum (ER)-associated degradation. The encoded protein removes unfolded proteins, accumulated during ER stress, by retrograde transport to the cytosol from the ER. This protein also uses the ubiquitin-proteasome system for additional degradation of unfolded proteins. Sequence analysis identified two transcript variants that encode different isoforms.

Community Annotation of SYVN1 Add / Edit SYVN1: Annotations

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Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


SYVN1 is highly significantly mutated in
SYVN1 is significantly mutated in
SYVN1 is near significance in

Click on a tumor type to see its full list of significant genes.

Data details

Mutation list for SYVN1