SYTL3 Back

synaptotagmin-like 3

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NCBI Description of SYTL3

The protein encoded by this gene belongs to the family of synaptotagmin-like proteins (SLPs). SLPs are peripheral membrane proteins that interact with RAB27A protein, and play a role in vesicular trafficking. Unlike, SLPs 1 and 2, this protein binds phospholipids in the presence of calcium ions. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Community Annotation of SYTL3 Add / Edit SYTL3: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

SYTL3 is highly significantly mutated in
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SYTL3 is significantly mutated in
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SYTL3 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


Mutation list for SYTL3