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synaptotagmin VII

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NCBI Description of SYT7
This gene is a member of the synaptotagmin gene family and encodes a protein similar to other family members that mediate calcium-dependent regulation of membrane trafficking in synaptic transmission. A similar protein in rodents mediates hormone secretion and lysosome exocytosis. In humans, expression of this gene has been associated with prostate cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Community Annotation of SYT7 Add / Edit SYT7: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

SYT7 is highly significantly mutated in
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SYT7 is significantly mutated in
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SYT7 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for SYT7