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synaptotagmin VII

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NCBI Description of SYT7

This gene is a member of the synaptotagmin gene family and encodes a protein similar to other family members that mediate calcium-dependent regulation of membrane trafficking in synaptic transmission. A similar protein in rodents mediates hormone secretion and lysosome exocytosis. In humans, expression of this gene has been associated with prostate cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Community Annotation of SYT7 Add / Edit SYT7: Annotations

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Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


SYT7 is highly significantly mutated in
SYT7 is significantly mutated in
SYT7 is near significance in

Click on a tumor type to see its full list of significant genes.

Data details

Mutation list for SYT7