SYT6 Back

synaptotagmin VI

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NCBI Description of SYT6
The protein encoded by this gene belongs to the synaptotagmin family. Synaptotagmins share a common domain structure that includes a transmembrane domain and a cytoplasmic region composed of 2 C2 domains, and are involved in calcium-dependent exocytosis of synaptic vesicles. This protein has been shown to be a key component of the secretory machinery involved in acrosomal exocytosis. Alternatively spliced transcript variants have been found for this gene.

Community Annotation of SYT6 Add / Edit SYT6: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

SYT6 is highly significantly mutated in
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SYT6 is significantly mutated in
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SYT6 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for SYT6