SYT2 Back

synaptotagmin II

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NCBI Description of SYT2

Synaptotagmins, like SYT2, are integral membrane proteins of synaptic vesicles thought to serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis (Hilbush and Morgan, 1994 [PubMed 8058779]).[supplied by OMIM, Mar 2008].

Community Annotation of SYT2 Add / Edit SYT2: Annotations

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Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


SYT2 is highly significantly mutated in
SYT2 is significantly mutated in
SYT2 is near significance in

Click on a tumor type to see its full list of significant genes.

Data details

Mutation list for SYT2