SYP Back

synaptophysin

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NCBI Description of SYP
This gene encodes an integral membrane protein of small synaptic vesicles in brain and endocrine cells. The protein also binds cholesterol and is thought to direct targeting of vesicle-associated membrane protein 2 (synaptobrevin) to intracellular compartments. Mutations in this gene are associated with X-linked mental retardation (XLMR).

Community Annotation of SYP Add / Edit SYP: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

SYP is highly significantly mutated in
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SYP is significantly mutated in
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SYP is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for SYP