SYNGR1 Back

synaptogyrin 1

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NCBI Description of SYNGR1
This gene encodes an integral membrane protein associated with presynaptic vesicles in neuronal cells. The exact function of this protein is unclear, but studies of a similar murine protein suggest that it functions in synaptic plasticity without being required for synaptic transmission. The gene product belongs to the synaptogyrin gene family. Three alternatively spliced variants encoding three different isoforms have been identified.

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

SYNGR1 is highly significantly mutated in
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SYNGR1 is significantly mutated in
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SYNGR1 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for SYNGR1