SYNE2 Back

spectrin repeat containing, nuclear envelope 2

External References:      Wikipedia GeneCards HUGO COSMIC Google Scholar

NCBI Description of SYNE2
The protein encoded by this gene is a nuclear outer membrane protein that binds cytoplasmic F-actin. This binding tethers the nucleus to the cytoskeleton and aids in the maintenance of the structural integrity of the nucleus. Several transcript variants encoding different isoforms have been found for this gene.

Community Annotation of SYNE2 Add / Edit SYNE2: Annotations

No community annotations yet for SYNE2.
Sort mutations by: Tumor type  Mutation type  Position  
Straightedge cursor Expand

Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

SYNE2 is highly significantly mutated in
(none)
SYNE2 is significantly mutated in
(none)
SYNE2 is near significance in
(none)

Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for SYNE2