SYCP3 Back

synaptonemal complex protein 3

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NCBI Description of SYCP3
This gene encodes an essential structural component of the synaptonemal complex. This complex is involved in synapsis, recombination and segregation of meiotic chromosomes. Mutations in this gene are associated with azoospermia in males and susceptibility to pregnancy loss in females. Alternate splicing results in multiple transcript variants that encode the same protein.

Community Annotation of SYCP3 Add / Edit SYCP3: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

SYCP3 is highly significantly mutated in
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SYCP3 is significantly mutated in
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SYCP3 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for SYCP3