SUV39H1 Back

suppressor of variegation 3-9 homolog 1 (Drosophila)

External References:      Wikipedia GeneCards HUGO COSMIC Google Scholar

NCBI Description of SUV39H1

This gene is a member of the suppressor of variegation 3-9 homolog family and encodes a protein with a chromodomain and a C-terminal SET domain. This nuclear protein moves to the centromeres during mitosis and functions as a histone methyltransferase, methylating Lys-9 of histone H3. Overall, it plays a vital role in heterochromatin organization, chromosome segregation, and mitotic progression.

Community Annotation of SUV39H1 Add / Edit SUV39H1: Annotations

Added by Deepak Jha

0

Sort mutations by: Tumor type  Mutation type  Position  
Straightedge cursor Expand

Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

SUV39H1 is highly significantly mutated in
(none)
SUV39H1 is significantly mutated in
(none)
SUV39H1 is near significance in
(none)

Click on a tumor type to see its full list of significant genes.

Data details


Mutation list for SUV39H1