SUMO3 Back

SMT3 suppressor of mif two 3 homolog 3 (S. cerevisiae)

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NCBI Description of SUMO3
SUMO proteins, such as SUMO3, and ubiquitin (see MIM 191339) posttranslationally modify numerous cellular proteins and affect their metabolism and function. However, unlike ubiquitination, which targets proteins for degradation, sumoylation participates in a number of cellular processes, such as nuclear transport, transcriptional regulation, apoptosis, and protein stability (Su and Li, 2002 [PubMed 12383504]).[supplied by OMIM, Mar 2008].

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

SUMO3 is highly significantly mutated in
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SUMO3 is significantly mutated in
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SUMO3 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for SUMO3