SULT1C2 Back

sulfotransferase family, cytosolic, 1C, member 2

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NCBI Description of SULT1C2
Sulfotransferase enzymes catalyze the sulfate conjugation of many hormones, neurotransmitters, drugs, and xenobiotic compounds. These cytosolic enzymes are different in their tissue distributions and substrate specificities. The gene structure (number and length of exons) is similar among family members. This gene encodes a protein that belongs to the SULT1 subfamily, responsible for transferring a sulfo moiety from PAPS to phenol-containing compounds. Two alternatively spliced transcript variants encoding different isoforms have been described for this gene.

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

SULT1C2 is highly significantly mutated in
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SULT1C2 is significantly mutated in
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SULT1C2 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for SULT1C2