STX8 Back

syntaxin 8

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NCBI Description of STX8

The gene is a member of the syntaxin family. The encoded protein is involved in protein trafficking from early to late endosomes via vesicle fusion and exocytosis. A related pseudogene has been identified on chromosome 12. Alternative splicing results in multiple transcript variants.

Community Annotation of STX8 Add / Edit STX8: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

STX8 is highly significantly mutated in
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STX8 is significantly mutated in
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STX8 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


Mutation list for STX8