STX3 Back

syntaxin 3

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NCBI Description of STX3

The gene is a member of the syntaxin family. The encoded protein is targeted to the apical membrane of epithelial cells where it forms clusters and is important in establishing and maintaining polarity necessary for protein trafficking involving vesicle fusion and exocytosis. Alternative splicing results in multiple transcript variants.

Community Annotation of STX3 Add / Edit STX3: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

STX3 is highly significantly mutated in
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STX3 is significantly mutated in
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STX3 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


Mutation list for STX3