STS Back

steroid sulfatase (microsomal), isozyme S

External References:      Wikipedia GeneCards HUGO COSMIC Google Scholar

NCBI Description of STS
The protein encoded by this gene catalyzes the conversion of sulfated steroid precursors to estrogens during pregnancy. The encoded protein is found in the endoplasmic reticulum, where it acts as a homodimer. Mutations in this gene are known to cause X-linked ichthyosis (XLI).

Community Annotation of STS Add / Edit STS: Annotations

No community annotations yet for STS.
Sort mutations by: Tumor type  Mutation type  Position  
Straightedge cursor Expand

Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

STS is highly significantly mutated in
(none)
STS is significantly mutated in
(none)
STS is near significance in
(none)

Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for STS